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Proficiency Testing Program for Hb E (HBB: c.79G>A) Screening in Thailand Using Lyophilized Hb E Control Materials.
Pornprasert S, Surajinda S, Pongpunyayuen P, Punyamung M, Ruengdit C, Intasai N. Pornprasert S, et al. Hemoglobin. 2020 Mar;44(2):82-85. doi: 10.1080/03630269.2020.1734612. Epub 2020 May 24. Hemoglobin. 2020. PMID: 32449408
The dichlorophenol-indophenol (DCIP) test and microcolumn chromatography are simple methods commonly used for screening of Hb E (HBB: c.79G>A) in Thailand. However, there is no proficiency testing (PT) program for these screening tests. ...
The dichlorophenol-indophenol (DCIP) test and microcolumn chromatography are simple methods commonly used for screening of Hb E (HBB: c …
Diagnosis of α0-thalassemia Chiang Rai (--CR) deletion by melt curve analysis in Northern Thailand.
Ruengdit C, Khamphikham P, Punyamung M, Pongpunyayuen P, Pornprasert S. Ruengdit C, et al. Scand J Clin Lab Invest. 2022 May;82(3):181-184. doi: 10.1080/00365513.2022.2040049. Epub 2022 Feb 21. Scand J Clin Lab Invest. 2022. PMID: 35188019

Among 4,952 blood samples, the assay was performed in 525 samples with a mean corpuscular volume (MCV) < 80 fL, HbA(2) < 3.5%, HbA(2)+E < 25%, and negative for common deletional alpha(0)-thalassemia --(SEA) and --(THAI). The developed method showed T(m) values of 85.8 0.

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Among 4,952 blood samples, the assay was performed in 525 samples with a mean corpuscular volume (MCV) < 80 fL, HbA(2) < 3.5%, HbA(2)+

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Multiplex Quantitative Real-Time Polymerase Chain Reaction and High-Resolution Melting Analysis for Identification of a Couple At-Risk of Having a Newborn with Severe Thalassemia.
Ruengdit C, Punyamung M, Khamphikham P, Pongpunyayuen P, Intasai N, Pornprasert S. Ruengdit C, et al. Hemoglobin. 2021 Sep;45(5):309-313. doi: 10.1080/03630269.2022.2028634. Epub 2022 Feb 9. Hemoglobin. 2021. PMID: 35139748
With this approach, 22 (7.2%) of 306 couples were diagnosed as being at-risk for having a child with severe thalassemia, including three homozygous alpha(0)-thal, five homozygous beta-thal and 14 Hb E (HBB: c.79G>A)/beta(0)-thal disease. Our findings indicated that mult …
With this approach, 22 (7.2%) of 306 couples were diagnosed as being at-risk for having a child with severe thalassemia, including three hom …